Role of the adrenal cortex
نویسندگان
چکیده
sYNoPsis Bilateral adrenalectomy produces a reduction in the alkaline phosphatase concentration in rat intestine, which is not prevented by the administration of saline, but is prevented by the administration ofcortisone. The administration of A.C.T.H. to normal rats leads to a rise in intestinal alkaline phosphatase levels associated with a small increase in the weight of the adrenals, while the administration of hydrocortisone produces large increases in the enzyme, even with doses which cause significant hypoplasia of the adrenal glands. The significance of these findings in relation to mechanisms of fat absorption and the treatment of steatorrhoea is discussed.
منابع مشابه
Effects of Type 1 and Type 2 Diabetes on Micro-Anatomical Changes of Adrenal Gland in Male Wistar Rats
Background & Aims: Changing the hormonal output of endocrine glands, diabetes leads to the occurrence of secondary metabolic disorders. Neuropathy, on the other hand, is the most common neurological complication of diabetes which affects the neuroendocrine system, in addition to peripheral and autonomic nervous system, contributing to exacerbation of disease severity. In this line, the present ...
متن کاملThe Role of the Endocannabinoids in Suppression of the Hypothalamic- pituitary-adrenal Axis Activity by Doxepin
Objective(s) The mechanism(s) by which antidepressants regulate the hypothalamic-pituitary-adrenal (HPA) axis remain elusive. The endocannabinoid system (eCBs) which exhibits antidepressant potential, appears to regulate the HPA axis activity. Therefore, we aimed to investigate the role of the eCBs in the action of doxepin including its effect on the HPA axis. Materials and Methods Male Wist...
متن کاملEffect of high concentration of testosterone enanthate on histometrical structure of the adrenal cortex in male rats
Testosterone enanthate (TE) is used by many athletes as a muscle builder. Previous studies showed that high concentration of the drug in plasma may affect the natural function of endocrine glands, specially the secretion of the adrenocortical hormones. The objective of the present study was to examine the effects of high concentration of TE on histometrical structure of adrenal cortex in male r...
متن کاملThe effects of subchronic social and isolation stresses on learning and memory trend in male rats
Introduction: Psychological stresses influence brain functions such as learning and memory. Environmental factors like types and durations of stress affect brain responsiveness. This study investigated the effects of two subchronic social and isolation stresses on learning, memory, adrenal glands weight and corticosterone levels in the hippocampus and frontal cortex. Methods: Eighteen male ...
متن کاملEffects of Noise Exposure on the Volume of Adrenal Gland and Serum Levels of Cortisol in Rat
Background: Noise pollution is considered as a stressful factor in every day’s life of the industrial world. The present study was designed to investigate the probable effects of different time exposure of noise stress on histomorphometric changes of adrenal gland, plasma cortisol and body weight of the rat. Methods: Sixty adult male Wistar rats were divided into two series of short time noise ...
متن کاملExposure to cell phone radiofrequency changes corticotrophin hormone levels and histology of the brain and adrenal glands in male Wistar rat
Objective(s): Nowadays, the electromagnetic field-emitting devices are used routinely in our lives. Controversial reports exist concerning the effects of mobile radiofrequency (RF) on different parts of the body, especially stress hormones. The main goal of the present work was to study the long-term effects of mobile RF900 MHz exposure with special focus on the adrenal gland pathophysiology an...
متن کامل